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Why 14 to 21 days and not longer: HGH is a 22 kDa protein, not a small peptide

I tried increasing the frequency of SI from 2 weekly to 1 weekly and the flushing got much worse - so I think this is the likely culprit

The only structural difference is the first amino acid: glycine vs alanine

(Injecting plain water in large volume would cause cells to swell and rupture due to osmotic imbalance, so sterile water is only given after adding an appropriate amount of solute to make it nearly isotonic

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That extra step can prevent confusion between micrograms, milliliters, and total vial contents