The increased MAO-A levels in chronic social stress result in decreased serotonin and dopamine release, playing a role in depression from chronic stress.[ref] MAO-A, MAOIs, and Tyramine: MAO enzymes, particularly MAO-A , are involved in the breakdown of tyramine, a naturally occurring amine found in certain foods
Cell Metabolism , 21(3), 443454
This distinction matters enormously for both safety and effectiveness
In-parallel metabolomic and proteomic measurements can broaden the interpretation of glutathione-pathway activity (Wasinger et al., 2025)
Because L-theanine tends to promote relaxation, while caffeine promotes alertness, the two have opposite but complementary effects
The other one we talk about is the mind, how you use your mind, and what we call mind state to approach life and how you're going to deal with challenges and everything