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Each of these can accelerate fluid loss

GLP-1s, or glucagon-like peptide-1 receptor agonists, work by stimulating insulin release, reducing appetite, and slowing gastric emptying, contributing to effective blood sugar control and weight management

It stimulates the NRF-2 pathway by inhibiting its repressor KEAP1 and promoting NRF-2 nuclear translocation

However, studies suggest the savings have not materialized yet

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

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