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To make it clear: Melanins primary function is to: But when melanin production becomes imbalanced, it leads to skin pigmentation disorders and hyperpigmentation concerns

Cost is the other major factor

Guglielmetti et al

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Local application of steroid such as dexamethasone mouthwash, tacrolimus, diphenhydramine and vitamin B are common prescriptions [18]

For individuals at moderate risk of gastrointestinal complications, combined therapy of NSAIDs with a gastroprotective agent should be considered