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Indeed, the apical localisation of SOP enzymes in human colonic crypts places this pathway optimally at the hostmicrobiome interface

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Figure 3 Activated IRE1 regulates gene expression by increasing ER protein folding capacity via TRAF2

Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE)