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Scientific research associates the peptide with activating the PER1 protein produced in the hypothalamus

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[2] Notable causes of neurogenic bladder include disorders of the central nervous system such as Parkinson's disease, multiple sclerosis, and spinal cord injuries as well as disorders of the peripheral nervous system such as diabetes mellitus, vitamin B12 deficiency, and alcohol-induced nerve damage

[3] NAD+ Injection is supplied by compounding pharmacies as a lyophilized (freeze-dried) sterile powder, typically in vials containing 500 mg of NAD+ per vial