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Cell-mediated immunity refers to all immune responses that are not antibody-driven (such as the activation of macrophages, the activation of natural killer cells, and cytokines that respond to antigens rather than antibodies)

doi: 10.4049/jimmunol.176.10.6022 85

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A recent post-hoc analysis of the 52-week, open-label extension phases of BIPARK I and II compared the longer-term outcome of subjects with a fluctuation history of 2 years or less (n = 227) between those who had received opicapone vs placebo in the initial double-blind phase of the trial

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