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448 A phase III trial (NCT02956486) assessing effectiveness and safety in early-stage AD patients was terminated due to an unfavorable risk-benefit ratio

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Consistent signaling: Encourages sustained lipolysis Reduces fat regain risk Supports long-term metabolic adaptation Interrupting that signal arbitrarily works against the goal

[DOI] [PMC free article] [PubMed] [Google Scholar] Yang H., Chen C., Chen H., Duan X., Li J., Zhou Y., et al

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(2002) Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)