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On the other hand, no significant differences were found in the Glu or GABA levels, or in the Glu/GABA ratio between the ASD and control groups, which is in line with a recent meta-analysis of MRS studies in adults with ASD [25]

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3.2 Curcumin: potential risks and challenges Despite numerous studies highlighting the potential benefits of CUR, certain adverse effects and toxicities have been reported, particularly at high doses or with prolonged use