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However, significant variations in control types (placebo, MET, or intensive lifestyle), concomitant medications, and follow-up windows mean that a robust head-to-head ranking of strategies is still lacking

A calculated estimate of insulin resistance using the homeostatic model assessment for insulin resistance (HOMA-IR) demonstrated a significant reduction in the HOMA-IR score to almost undetectable levels with RETA treatment, an approximation suggesting a loss of insulin resistance (Supplementary Fig

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