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24 With respect to this, the negative association between frequency of the cSHMT -C1420T variant and latitude documented in this study may indicate that activity of the de novo thymidylate synthesis pathway is increasingly impaired in populations exposed to higher UVR, but the burden of this variant is unclear due to mSHMT likely maintaining cSHMT activity in such cases

The gut microbiota modulates host energy and lipid metabolism in mice

However, there were some notable observations that may have been impacted by the probiotic supplement after antimicrobial treatment compared to placebo (visit 3)

Quantification of GL13-stained sections confirmed these observations (Fig