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Some important notes on the dosage and administration of Neurobion: The duration of treatment depends on the severity of the condition and the patient's response, or as prescribed by the doctor

NNMT depletes the NAD+ precursor pool by methylating nicotinamide the same nicotinamide that the salvage pathway would otherwise convert back into NAD+ via the enzyme NAMPT

While there is no safe upper limit (because B12 is water soluble so you pee out anything you don't need), the NHS advises people not to take too much as it could be harmful

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