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In mice, p-STAT3-S727, but not p-STAT3-Y705, was dramatically increased in GCGR-KO cells (Fig

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Reviewed PARP1 hyperactivation as a driver of NAD+ depletion in DNA damage models and the basis for NAD+ supplementation research in premature ageing syndromes

More importantly, the study demonstrated that this healing continued for a sustained period (72 days) whilst maintaining the functional restoration (Staresinic et al