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Insulin resistance is at the core of PCOS, which leads to hyperandrogenism and problems with ovulation

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Inhibition of these non-oxidative pathwaysincluding glycolysis, the PPP, and HIF/mTORC1 signalingconsistently reduces viral replication, whereas interventions that enhance glycolysis or suppress mitochondrial activity worsen disease ( Beyond the acute phase of infection, mitochondrial dysfunction persists across multiple tissues