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26 A review of 17 clinical studies of various trial designs, including pro- and retrospective, concluded that B12, particularly subcutaneously injected mB12 [methyl-B12], improves metabolic abnormalities in ASD along with clinical symptoms

Oral B12 supplementation is more accessible and cost-effective but relies on gastric intrinsic factor for absorption, rendering it unsuitable for individuals with gastric disorders or malabsorption syndromes

2019 Update: My vitamin B12 recommendations have changed to reflect the latest science and labeling changes

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