For those currently using semaglutide or tirzepatide who want to transition to retatrutide, a washout period between discontinuing the current peptide and initiating retatrutide is advisable
Not only did patients regain weight (with significant fat regain), which is normal following GLP-1 cessation, but the bimagrumab arms also saw patients *lose lean mass* following cessation, such that bimagrumab patients ended with a similar overall lean mass loss to patients in the semaglutide alone arms (even as the sema arms *regained* some lean mass)
Key Findings from the study: The report cites the U.S
It also helps buffer toxic acyl-CoA metabolites and supports mitochondrial health and function
NICE obesity guidance recommends evidence-based interventions including dietary change, physical activity, and licensed medications such as orlistat or semaglutide
You can switch your plan anytime when you log in online or through the app