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GLP-1 medications work partly by suppressing appetite

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29 in the journal JAMA Network Open

This accelerates intestinal transit time, meaning food passes through your digestive system faster than usual

It influences upstream biological conditions that regulate natural GLP-1 secretion: SCFA-mediated receptor activation (FFAR2/3) Mucosal barrier stability Reduced inflammatory tone Improved enteroendocrine cell signaling GLP-1 is a hormone

AT received honoraria from Boehringer Ingelheim, and research funding from GlaxoSmithKline and Takeda