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Am J Epidemiol, 142: 23-35

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* Correspondence: Chooi Ling Lim, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The appearance of drusen, typically following the formation of BLamD, further disrupts RPE organization, placing both mechanical and physiological stress on the surrounding RPE cells, which results in cell death [29]

Full healing cycles typically require eight to twelve weeks for optimal collagen remodeling and tissue repair

Family studies have demonstrated that blood pressure shows substantial heritability, suggesting that genetic factors contribute to hypertension