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This increase is likely related to GH's effect on skin cell proliferation and collagen synthesis [15]

The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution

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Hair and nail quality improvements are occasionally reported in this window, likely reflecting improved keratinocyte antioxidant status

By contrast, ICA exerted no protective effect in GPX4-silenced SW1353 cells, indicating that the drug ameliorates ferroptosis and cartilage injury via the SLC7A11/GPX4 pathway (153)

Further exploration could lead to strategies for its use in age-related atrophy and impaired regeneration, although at this stage we have not provided direct evidence that LASSS oral-supplementation can mitigate sarcopenia or has therapeutic value, awaiting the results of aging experiments