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Healthcare professionals should educate patients thoroughly on proper technique, and patients should feel empowered to ask questions or request refresher training at any time

Dose-dependent reductions in HbA1c caused by tirzepatide (5, 10, and 15 mg) are significantly higher than those caused by various comparators, including placebo, semaglutide, insulin degludec, insulin glargine, and placebo with background insulin [75]

Denials cluster around a handful of causes

10mg is used when greater glycaemic control is needed or in patients who tolerate the 5mg dose well

Hypoglycaemia risk is very low with incretin mimetics when used alone, but sulfonylureas carry significant hypoglycaemia risk, especially in elderly patients or those with renal impairment

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