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The double-stranded DNA homology-directed repair (HDR) template (HiBiTBRD4 with extensions, shown below), the RNP complex and an electroporation enhancer (Integrated DNA Technologies) were then electroporated into Jurkat cells using an Amaxa 4D-Nucleofector (Lonza)

In clinical trials, burping (also known as eructation) occurred in around 7% of people taking 2.4 mg of Wegovy weekly for obesity

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