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"I'm very concerned about doing this in a way that is healthy for me, not just my relationship with gravity represented by a scale, but my actual physical body composition," she says

Beverages that combine both carbohydrates and electrolytes such as juice, coconut water, or sports drinks seem to have the most potent effect on boosting hydration, according to one study

Del Prato S, Kahn SE, Pavo I, Weerakkody GJ, Yang Z, Doupis J, et al

Orforglipron also is more likely to increase heart rate (by about 4 beats per minute)

Pelitera agrees the small sample size is a limitation of the research

414 Together, these effects contribute to the protection of dopaminergic neurons (source)