It is critical to remember that low zinc levels have a wide impact on the immune system [91, 92] and that zinc itself may reduce viral replication, including SARS-CoV-2 replication [93]
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Summary of preclinical works Pretreatment with nicotinamide mononucleotide, an NAD precursor derived from niacin, in rats exposed to HS results in a decrease in interleukin 6 (IL-6) and venous lactates, and in the preservation of mitochondrial respiration assessed by high-resolution respirometry