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While concerns regarding the carcinogenicity of plastic particles have been raised, the majority of existing studies predominantly assess acute toxicity and seldom address long-term outcomes such as carcinogenesis

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Most published human data covers the parent CJC-1295 sequence, with several Phase 1 studies and one halted Phase 2 trial

Dose and Frequency of Use Higher and more frequent dosing may saturate tissues and prolong the duration of activity