and I think this is a big emerging DDI between PPIs and GLP-1 drugs that needs to be studied more
However, recent clinical and research findings indicate that vitiligo is caused by the body's immune system attacking melanocytes, the cells responsible for skin colour, not only in the skin but also in mucous membranes, the eyes, hair follicles, and the ears
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Intracellular concentrations range from 1-10 mM, making it one of the most concentrated metabolites in mammalian cells
This entire process is highly dependent on cellular energy, requiring adenosine triphosphate (ATP) to function correctly
Even with proper supplementation and a nutrient-rich diet, some GLP-1 patients still reduce their overall food intake enough to create gaps in key nutrients, such as vitamin D, B12, and protein, that are critical for maintaining skin elasticity, hydration, and overall resilience