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Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae
doi: 10.1016/S0140-6736(18)32590-X
To maintain results, a healthy diet and regular exercise are recommended
The crosstalk between these cells is a crucial link in the chain of events that transforms toxic exposures into neurological symptoms
follow clinical guidance for any accompanying blood tests GSTT1 encodes glutathione Stransferase Theta 1, a cytosolic phase II detoxification enzyme in the Theta class of the glutathione Stransferase (GST) superfamily
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