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"Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69"

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The mechanisms here are less well characterized than in musculoskeletal tissue, but the consistent finding of preserved dopaminergic tone in BPC-157-treated animals has generated interest in potential applications for neurodegenerative conditions

During aging, the structure and function of the hematopoietic niche are significantly altered, along with the abnormal composition of stromal cells, leading to a weakened ability to support HSCs