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Following this pattern, TMEV-infected SJL/J mice treated orally with this same antibiotic mixture showed protection against motor dysfunction, axonal damage, and CNS immune infiltration, likely through enhanced CD4 + CD39 + T cells, CD5 + CD1d + B cells, and downregulated IL-17 in the periphery (Mestre et al., 2019)

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Moreover, the MRP family of proteins is made up of 9 transporters (MRP1-MRP9), almost all of which accept glutathione S conjugates as substrates