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Furthermore, ferroptosis inhibition reversed IL-1-induced alteration in VE-cadherin distribution along the EC junction (Fig

(5.9 ) Risk of Thyroid C-Cell Tumors In mice and rats, semaglutide caused a dose-dependent and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure at clinically relevant plasma exposures [see Nonclinical Toxicology (13.1 )]

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