This is because, in the early stages of their release, there were apprehensions regarding their possible association with both pancreatitis and pancreatic cancer
Most users experience: 714 days: Fresh, glowing skin 24 weeks: Visible reduction in pigmentation 48 weeks: Noticeable skin whitening 812 weeks: Full-body glow and even tone Smokers or people with high sun exposure may require longer usage for optimal results
What we found: the promise sounds compelling, but the evidence isn't there yet
Cardiovascular Outcomes Data The SELECT trial (N=17,604) published in the New England Journal of Medicine in 2023 showed that semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% versus placebo in adults with overweight or obesity and established cardiovascular disease, over a mean follow-up of 34 months [11]
METABOLIC DYSFUNCTION ASSOCIATED STEATOTIC LIVER DISEASE (MASLD) AND METABOLIC DYSFUNCTION ASSOCIATED STEATOHEPATITIS (MASH) Numerous studies have shown that treatment with SGLT-2 inhibitors decrease liver enzymes (107,199-203)