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Observations of variable lean mass outcomes and dietary shifts during GLP-1RA therapy [40, 75] suggest that substrate availability may influence therapeutic durability even in the absence of overt deficiency
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This metabolic cascade yields lipid oxidation products such as 4HNE and oxPLs [33, 34].Glutathione peroxidase 4 (GPX4), a pivotal antioxidant enzyme, functions as the core regulator of ferroptosis through the suppression of lipid peroxidation
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