In the last years, a link between gut microbiota composition and autoimmune diseases has been proven in murine models and hypothesized in humans owed to the interactions with both the innate and adaptive branches of immunity [179]
Big Pharma is still piling in: Pfizer closed its 2023 $43B Seagen deal to expand its ADC platform, and PD-1 biosimilars are expected to arrive late-decade, expanding access rather than collapsing the category, as CRA Insights noted
However, severe or persistent tiredness beyond 8 weeks may indicate an individual response requiring dose adjustment or medication switch
Nutrients 15:661
So, Andrew, I think, you've also highlighted, you know, this market broadening, especially beyond the large cap leaders, even as AI investment continues, I think, as you touched on earlier
Nutrients 5:525542 Gaschler MM, Stockwell BR (2017) Lipid peroxidation in cell death