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For nuclear and cytosolic targeting, we used histone H2B and a nuclear export sequence (NES), [3,40] respectively

Finally, individuals with compromised liver or kidney function, or those with severe gastrointestinal diseases like Crohn's or ulcerative colitis, require highly modified protocols

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That's because the drugs don't simply facilitate weight-loss

A wide array of surfactants, bile salts, fatty acids, and chelating agents was evaluated for their ability to increase paracellular or transcellular transport (Maher et al., 2016)