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Incidence, patterns of progression, and outcomes of preexisting and newly discovered brain metastases during treatment with anti-PD-1 in patients with metastatic melanoma

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That brings us to the second and arguably most urgent issue facing the field: the complete absence of validated biomarkers for patient selection, durability prediction, inflammation trajectories, neuroprotective potential, or combination-therapy optimization

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Keep detailed records of each injection, including the time, dosage, injection site, and any observed effects

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