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Its fair to assume that in GLP-1 patients undergoing significant weight loss it will be even less predictable, Byrne said.

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Wegovy requires vigilance for serious adverse effects including pancreatitis (severe persistent abdominal pain radiating to the back), gallbladder disease (right upper quadrant pain, fever, jaundice), and in people with diabetes, diabetic retinopathy and risk of dehydration/acute kidney injury

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