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The pricing, the insurance, and the value all factor into the overall cost of long-term therapy and each should be considered against the alternatives and possible health benefits

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15 Although the primary function of GLP-1 is to serve as an anorexigenic (appetite-reducing) and incretin hormone, as well as a mediator of the ileal brake through inhibition of upper gastrointestinal function to prevent malabsorption and postprandial metabolic disturbances, the influence of GLP-1 on colon function was evaluated by a limited number of studies