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By combining MRS findings with clinical observations over time (regarding, for instance, treatment resistance and relapse/remission), the information becomes even more powerful in translation. In one current study, the team has used MRS to study functional deterioration in the brain after relapse of psychotic disorders
This may reflect a rapid cellular uptake of the TAT-GFP fusion protein, leading to low detectable concentrations in the bloodstream despite its effective distribution in peripheral tissues
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If the powder does not dissolve after 5 minutes of gentle rolling, the vial may have been improperly stored before reconstitution
