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561 fludrocortisone, a mineralocorticoid that promotes sodium and water retention to expand plasma volume, though it must be used cautiously due to the risk of supine hypertension and hypokalemia

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This cytoprotective effect involves upregulation of antioxidant defense systems and stabilization of mitochondrial function, with Dihexa-treated cells maintaining healthier mitochondrial membrane potentials under stress conditions

This process helps the skin appear brighter and more even-toned