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Do not double the dose

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They do not replace thyroid hormone GLP-1 medications do not improve thyroid hormone production

12,14 Manufacturer/Sponsor In consultation with Health Canada, review current data and consider inclusion of the risk of delayed gastric emptying in the Serious Warnings and Precautions box in the product monograph, as well as in any consumer-facing information

We recognize the dual benefits of these medications, not only in improving glycemic control but also in aiding weight loss by promoting satiety and slowing gastric emptying

452 Endothelial cells exhibit enhanced NO production and concurrent suppression of endothelin formation, resulting in vascular smooth muscle relaxation and vasodilation mediated by the endothelium (e.g., GLP-1, exenatide, and liraglutide)