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Women with preterm births have also been found to have significantly decreased PON 1 activity in comparison to controls [254]

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doi: 10.1210/jc.2012-1230

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As pharmacological agents may have more targeted mechanisms of action as compared to NPIs, precision approaches to combination interventions will need to be guided by an analysis of an individuals biological makeup, including, optimally, genetic risk factors and multiomics perturbations that have been linked to specific disease pathways or susceptibility