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When appetite suppression plateaus or side effects emerge, the solution is dose adjustmentmoving from 0.25 mg to 0.5 mg weekly, for examplenot frequency changes

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Tirzepatide is unique because it acts as a dual agonist, targeting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

GIP (Glucose-dependent insulinotropic polypeptide): Enhances insulin secretion after eating and supports fat metabolism