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Tirzepatide for metabolic dysfunction-associated steatohepatitis with liver fibrosis

IRF3 enhances the interaction between YAP and TEAD4 in the nucleus, promoting nuclear translocation and activation of YAP (Jiao et al., 2018)

Glycolysis and decidualization Once incorporated into the cells, glucose is subsequently degraded by several pathways: lactate production, or oxidation by the Krebs cycle and the respiratory chain in the mitochondria to provide energy as ATP, or glycolytic bypass metabolic pathways

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Arch Med Res 38:948 Raftos JE, Whillier S, Kuchel PW (2010) Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data

Metabolomics data are provided in the Supplementary Tables 3, 4