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2023 May;29(5):305-340 Byrne RA, Rossello X, Coughlan JJ, et al

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Ammonia readily crosses the blood-brain barrier and is thought to inhibit glutamate uptake, thereby increasing extracellular glutamate concentrations in the brain and resulting in activation of NMDA receptors

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The CAS number for PT-141 is 189691-06-3