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Comment: Commenters stated that the proposals would create distortions in the MS-DRG relative weights and that CMS has not modelled the impacts of or otherwise accounted for these distortions in the proposed policy

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Running alongside these is TRIUMPH-CVOT, a separate cardiovascular outcomes trial enrolling around 10,000 participants with established cardiovascular disease over 3-4 years

95% CI, 0.630.88), indicating a significant survival benefit