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Glaxo Smith Kline sponsored meta analysis phase III randomized clinical trials, with a study duration of 2 years demonstrated that in a population with symptomatic BPH and/or at increased risk of prostate cancer, a statistically significant lower number of detectable prostate cancers was found in men taking dutasteride compared to control groups

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Future perspectives and research directions TM research depends on the strategic incorporation of conventional knowledge systems with modern scientific methodologies

To minimize side effects (lung toxicity, ototoxicity, nephrotoxicity) some pediatric protocols used reduced dose of bleomycin from once per week to once per cycle (PEb) [322,323,324] or carboplatin instead of cisplatin [325, 326]

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