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The second is neural, where GLP-1 activates vagal nerve afferents in the gut wall that transmit satiety signals directly to the nucleus tractus solitarius (NTS) in the brainstem
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doi: 10.1097/MD.0000000000026086 45 ZhangFChenZWuDTianLChenQYeYet al
According to results from a multinational survey interviewing 3742 diabetic patients, an oral antidiabetic drug is preferable as the first choice of medication and medications for long-term use, especially for those with high HbA1c and comorbidities (obesity, hypertension, dyslipidaemia) [96]
Use clean technique, a new needle for each injection, and a sharps container for disposal
The gastrointestinal symptoms occur primarily because GLP-1 receptor agonists slow gastric emptying, meaning food remains in the stomach for longer periods
