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In the later stages of pressure overload, administration of the mitochondrial-targeted superoxide dismutase (SOD) mimetic mitoTEMPO can partially restore mitochondrial respiration and cardiac contractility by partially restoring LONP1 activity, but in vivo knockdown of LONP1 can partially counteract this protective effect [67]

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First, it appeared to calm inflammation: irritating a rat's nose with capsaicin the compound that makes chilli peppers hot produced a reaction that BPC-157 blunted, with a "dose-dependent protective effect" [6]

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Cancer 122 , 279292 (2020)