During ripening, climacteric fruits show an increase in ethylene production and respiration rate that significantly hasten their postharvest decay (Zenoni et al., 2023)
Were very careful with that
Then, across 50+ clinical studies in major neurocognitive disorders including Alzheimers dementia, Parkinsons disease & Lewy-body dementia, and other cognitive deficits, despite some inconsistencies and translational gaps, they found that the overall evidence seems encouraging and possibly even suggestive of GLP-1RAs disease-modifying properties in dementia
The first of such dual-agonist, MAR709, shows nearly balanced activity at both target receptors and improves body weight and glycemia with greater potency relative to pharmacokinetically-matched GLP-1 in rodents with diet- and genetically induced obesity (126)
Semaglutide markedly decreased body weight (Fig
Weight loss itself reduces intra-glomerular pressure and proteinuria