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In contrast, another study has shown that higher doses of LA (100 mg/kg body weight) for different durations (7 and 14 days) can produce better effects in improving the fat contents in the liver, and even the effects of aging, which depresses the effect of LA on improving fatty liver, can be easily abolished by adding LA

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27) suggest that selectivity for individual TrxRs can be attainable, which may result in lower toxicity

Therapeutic response to cyanocobalamin may decrease due to elderly age, infection, renal insufficiency, diabetes mellitus, marrow suppressants use (e.g