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Finally, all the treatment groups, except melatoninbetaine, GAbetaine, and melatoninGA, significantly increased renalase levels

Journal of Physiology & Pharmacology, 72(4), 543556

Barretina, J

Retrieved September 17, 2022

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Furthermore, the problems associated with vitamin C and E derivatives (e.g., limited tissue retention, targeting to the active site of oxidative stress, no targeting to specific ROS, and poor interaction with specific carriers) will largely also apply to these substances (especially because they structurally resemble vitamin C and E and share similar mechanisms of action)